Frataxin Antikörper (Middle Region)

Produktnummer ABIN2783174

Dieses Anti-Frataxin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Frataxin in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für Frataxin Antikörper (Middle Region) (ABIN2783174)

Target: Frataxin (FXN)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Frataxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Frataxin Antikörper

Bindungsspezifität: Middle Region

Sequenz: TLDNPSSLDE TAYERLAEET LDSLAEFFED LADKPYTLED YDVSFGDGVL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 207 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Frataxin

Target: Frataxin (FXN)

Andere Bezeichnung: Fxn

Hintergrund: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1.
Alias Symbols: FA, FARR, Frda, X25
Protein Size: 207

Molekulargewicht: 23 kDa

Gen-ID: 14297

NCBI Accession: NM_008044, NP_032070

UniProt: O35943

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size